• Product NameEHT 1864
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityEHT 1864 is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.
• Target NameRho inhibitor
• CAS No. 754240-09-0
• Calculated MW 581.47
• Formulation C25H29Cl2F3N2O4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system/ Cancer
  SMILES:FC(F)(F)C1=CC2=NC=CC(SCCCCCOC3=COC(CN4CCOCC4)=CC3=O)=C2C=C1
  Pathways:Cell Cycle/Checkpoint
  Receptor:Rac1; Rac1b; Rac2; Rac3
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL warmed (171.97 mM)Ethanol:<1 mg/mL (<1 mM)Water:100 mg/mL (171.97 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shutes A, et al. J Biol Chem. 2007, 282(49), 35666-35678.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting