• Product NameEmbelin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityEmbelin, a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 uM.
• Target NameIAP inhibitor; Lipoxygenase inhibitor; Prostaglandin Receptor inhibitor
• CAS No. 550-24-3
• Calculated MW 294.39
• Formulation C17H26O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O
  Pathways:Apoptosis; GPCR/G Protein; Metabolism
  Receptor:XIAP; 5-Lipoxygenase; mPGES-1
  Boling pt:
  Melting pt:
  Solubility:DMSO:59 mg/mL (200.41 mM)Ethanol:12 mg/mL (40.76 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nikolovska-Coleska Z, et al. J Med Chem, 2004, 47(10), 2430-2440.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting