• Product NameFludarabine Phosphate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityFludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 75607-67-9
• Calculated MW 365.21
• Formulation C10H13FN5O7P
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(N=C2N)F
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA polymerase α; DNA polymerase δ
  Boling pt:
  Melting pt:
  Solubility:Water: 2 mg/mL warmed (5.47 mM); DMSO: 73 mg/mL (199.88 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Huang P, et al, J Biol Chem, 1990, 265(27), 16617-16625.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting