• Product NameHO-3867
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityHO-3867, an analog of curcumin, is a selective STAT3 inhibitor.
• Target NameSTAT inhibitor
• CAS No. 1172133-28-6
• Calculated MW 464.55
• Formulation C28H30F2N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC1(N(C(C(=C1)CN2C/C(=C\C3=CC=C(C=C3)F)/C(=O)/C(=C/C4=CC=C(C=C4)F)/C2)(C)C)O)C
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 6 mg/mL warmed (12.91 mM); DMSO: 13 mg/mL warmed (27.98 mM)
  Appearance:YellowPowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Selvendiran K, et al. Y Biol Ther. 2011, 12(9), 837-845.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting