• Product NameIbutilide Fumarate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityIbutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.
• Target NameSodium Channel inhibitor
• CAS No. 122647-32-9
• Calculated MW 885.23
• Formulation (C20H36N2O3S)2.C4H4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.CCCCCCCN(CC)CCCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.C(=C/C(=O)O)\C(=O)O
  Pathways:Membrane transporter/Ion channel
  Receptor:Sodium Channel
  Boling pt:
  Melting pt:
  Solubility:DMSO:89 mg/mL (100.53 mM)Ethanol:89 mg/mL (100.53 mM)Water:89 mg/mL (100.53 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Simon A, et al.Europace. 2016 Mar 22.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting