• Product NameIndoximod (NLG-8189
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityIndoximod (NLG-8189), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression. Phase 2.
• Target NameIDO inhibitor
• CAS No. 110117-83-4
• Calculated MW 218.25
• Formulation C12H14N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)N
  Pathways:Metabolism
  Receptor:IDO
  Boling pt:
  Melting pt:
  Solubility:DMSO:1 mg/mL warmed (4.58 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hou DY, et al. Cancer Res. 2007, 67(2), 792-801.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting