• Product NameIstradefylline
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityIstradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.
• Target NameAdenosine Receptor antagonist
• CAS No. 155270-99-8
• Calculated MW 384.43
• Formulation C20H24N4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)OC)C
  Pathways:GPCR/G Protein
  Receptor:A2A
  Boling pt:
  Melting pt:
  Solubility:DMSO:6 mg/mL (15.6 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chen JF, et al. J Neurosci, 2001, 21(10), RC143.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting