• Product NameJZL184
• Brief DescriptionInhibitors
• Purification97.60%
• Biological ActivityJZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.
• Target NameLipase inhibitor
• CAS No. 1101854-58-3
• Calculated MW 520.49
• Formulation C27H24N2O9
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:OC(C1CCN(CC1)C(=O)OC1=CC=C(C=C1)[N+]([O-])=O)(C1=CC=C2OCOC2=C1)C1=CC=C2OCOC2=C1 |c:14,16,30,41,t:12,22,24,33,35|
  Pathways:Metabolism
  Receptor:MAGL
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (192.12 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Long JZ, et al. Nat Chem Biol, 2009, 5(1), 37-44.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting