• Product NameML324
• Brief DescriptionInhibitors
• Purification98.22%
• Biological ActivityML324 is a selective inhibitor of jumonji histone demethylase (JMJD2) with IC50 of 920 nM.
• Target NameHistone Demethylase inhibitor
• CAS No. 1222800-79-4
• Calculated MW 349.43
• Formulation C21H23N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)CCCNC(=O)C1=CC=C(C=C1)C1=CC2=CC=CN=C2C(O)=C1 |c:11,13,20,22,26,t:9,16,18|
  Pathways:Chromatin/Epigenetic
  Receptor:JMJD2
  Boling pt:
  Melting pt:
  Solubility:DMSO:43 mg/mL warmed (123.05 mM)Ethanol:3 mg/mL warmed (8.58 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Rai G, et al. Probe Reports from the NIH Molecular Libraries Program, 2010-2012.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting