• Product NamePirarubicin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent.
• Target NameTopoisomerase inhibitor
• CAS No. 72496-41-4
• Calculated MW 627.64
• Formulation C32H37NO12
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:[H][C@]1(CCCCO1)O[C@H]1[C@@H](N)C[C@H](O[C@@]2([H])C[C@@](O)(CC3=C2C(O)=C2C(=O)C4=C(C=CC=C4OC)C(=O)C2=C3O)C(=O)CO)O[C@H]1C |r,c:21,31,33,41,t:25,29|
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:
  Melting pt:
  Solubility:DMSO:7 mg/mL (11.15 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sugiyama T, et al. Jpn J Cancer Res, 1999, 90(7), 775-780.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting