• Product NameRBC8
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityRBC8 is a selective inhibitor of the GTPases RalA and RalB by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases Ras and RhoA.
• Target NameGTPase inhibitor
• CAS No. 361185-42-4
• Calculated MW 424.45
• Formulation C25H20N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:COC1=CC(C2C3=C(NN=C3OC(N)=C2C#N)C2=CC3=CC=CC=C3C=C2)=C(OC)C=C1
  Pathways:GPCR/G Protein
  Receptor:GTPases RalA; GTPases RalB
  Boling pt:
  Melting pt:
  Solubility:DMSO: 84 mg/mL (197.9 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Yan C, et al. Nature. 2014, 515(7527), 443-447.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting