• Product NameSB269970 HCl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySB269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3, exhibits >50-fold selectivity against other receptors.
• Target Name5-HT Receptor antagonist
• CAS No. 261901-57-9
• Calculated MW 388.95
• Formulation C18H28N2O3S.HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CC1CCN(CC[C@H]2CCCN2S(=O)(=O)C2=CC=CC(O)=C2)CC1 |r,c:18,21,t:16|
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT7
  Boling pt:
  Melting pt:
  Solubility:DMSO:11 mg/mL (28.28 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hagan JJ, et al. Br J Pharmacol, 2000, 130(3), 539-548.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting