- Product NameSB705498
- Brief DescriptionInhibitors
- Purification99.90%
- Biological ActivitySB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Phase 2.
- Target NameTRP/TRPV Channel antagonist
- CAS No. 501951-42-4
- Calculated MW 429.23
- Formulation C17H16BrF3N4O
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;