• Product NameSH-4-54
• Brief DescriptionInhibitors
• Purification99.76%
• Biological ActivitySH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5, respectively.
• Target NameSTAT inhibitor
• CAS No. 1456632-40-8
• Calculated MW 610.59
• Formulation C29H27F5N2O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(CC(=O)N(CC1=CC=C(C=C1)C1CCCCC1)C1=CC=C(C=C1)C(O)=O)S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3; STAT5
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 50 mg/mL warmed (81.88 mM); DMSO: 100 mg/mL (163.77 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Haftchenary S, et al. ACS Med Chem Lett. 2013, 4(11), 1102-1107.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting