• Product NameSirtinol
• Brief DescriptionInhibitors
• Purification99.96%
• Biological ActivitySirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively.
• Target NameSirtuin inhibitor
• CAS No. 410536-97-9
• Calculated MW 394.47
• Formulation C26H22N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C1=CC=CC=C1)NC(=O)C2=CC=CC=C2N/C=C/3\C(=O)C=CC4=CC=CC=C43
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT1; SIRT2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 23 mg/mL (58.3 mM)
  Appearance:YellowPowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting