• Product NameSofosbuvir (PSI-7977, GS-7977)
• Brief DescriptionInhibitors
• Purification99.82%
• Biological ActivitySofosbuvir (PSI-7977, GS-7977) is a HCV NS5B polymerase inhibitor for the treatment of chronic hepatitis C virus (HCV) infection.
• Target NameHCV Protease inhibitor
• CAS No. 1190307-88-0
• Calculated MW 529.45
• Formulation C22H29FN3O9P
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C[C@@H](C(=O)OC(C)C)NP(=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
  Pathways:Microbiology&virology; Proteases/Proteasome
  Receptor:HCV
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL warmed (188.87 mM)Ethanol:100 mg/mL (188.87 mM)Water:11 mg/mL warmed (20.77 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Murakami E, et al. J Biol Chem, 2010, 285(45), 34337-34347.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting