• Product NameTasquinimod
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityTasquinimod is an orally active antiangiogenic agent by allosterically inhibiting HDAC4 signalling. Phase 3.
• Target NameHDAC inhibitor
• CAS No. 254964-60-8
• Calculated MW 406.36
• Formulation C20H17F3N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C2C(=CC=C1)N(C)C(=O)C(C(=O)N(C)C1=CC=C(C=C1)C(F)(F)F)=C2O |c:4,6,20,22,28,t:2,18|
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC4
  Boling pt:
  Melting pt:
  Solubility:DMSO:81 mg/mL (199.33 mM)Ethanol:11 mg/mL warmed (27.06 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Isaacs JT, et al. Cancer Res.?013, 73(4), 1386-1399.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting