• Product NameBI-7273
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBI-7273 is a potent, selective, and cell-permeable BRD9 BD Inhibitor.
• Target NameEpigenetic Reader Domain inhibitor
• CAS No. 1883429-21-7
• Calculated MW 353.41
• Formulation C20H23N3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=CC(=CC(OC)=C1CN(C)C)C1=CN(C)C(=O)C2=C1C=CN=C2 |c:4,8,21,24,26,t:2,15|
  Pathways:Chromatin/Epigenetic
  Receptor:BRD7; BRD9
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 70 mg/mL (198.07 mM) DMSO: 70 mg/mL (198.07 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Martin LJ, et al. Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem. 2016 May 26;59(10):4462-75.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting