• Product NameCPI-637
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.
• Target NameEpigenetic Reader Domain inhibitor
• CAS No. 1884712-47-3
• Calculated MW 386.45
• Formulation C22H22N6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C[C@@H]1CC(=O)NC2=CC=CC(=C2N1)C3=CC4=C(C=C3)N(N=C4C5=CN(N=C5)C)C
  Pathways:Chromatin/Epigenetic
  Receptor:BRD4; CBP; EP300
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mL DMSO: 27 mg/mL (69.86 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Taylor AM, et al. ACS Med Chem Lett. 2016, 7(5):531-6.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting