• Product NameDyngo-4a
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1?μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively.
• Target NameDynamin inhibitor
• CAS No. 1256493-34-1
• Calculated MW 338.31
• Formulation C18H14N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC=C2C=C(C(=CC2=C1)C(=O)NN/C=C/3\C=C(C(=O)C=C3O)O)O
  Pathways:Cytoskeletal Signaling
  Receptor:DynI (brain); DynI (rec); DynII (rec)
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 1 mg/mL warmed (2.95 mM)DMSO: 67 mg/mL (198.04 mM)Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Harper CB., Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors. Trends Cell Biol. 2013 Feb;23(2):90-101.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting