• Product NameFatostatin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityFatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
• Target NameNPC1L1 inhibitor
• CAS No. 298197-04-3
• Calculated MW 375.33
• Formulation C18H18N2SHBr
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCCC1=NC=CC(=C1)C2=NC(=CS2)C3=CC=C(C=C3)C
  Pathways:Membrane transporter/Ion channel
  Receptor:SREBPs
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 58 mg/mL (154.53 mM) DMSO: 7 mg/mL (18.65 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kamisuki S, et al. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chem Biol. 2009, 16(8):882-92.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting