• Product NameGGTI 298
• Brief DescriptionInhibitors
• Purification98.15%
• Biological ActivityGGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis.
• Target NameTransferase inhibitor
• CAS No. 1217457-86-7
• Calculated MW 593.66
• Formulation C27H33N3O3SC2HF3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC3=CC=CC=C32.C(=O)(C(F)(F)F)O
  Pathways:Metabolism
  Receptor:GGTase I
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (168.44 mM); DMSO: 100 mg/mL (168.44 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sun J, et al. J Biol Chem. 1999, 274(11):6930-4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting