• Product NameHA15
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityHA15 is a molecule that targets specifically BiP/GRP78/HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
• Target NameGPR inhibitor; HSP inhibitor; Others inhibitor
• CAS No. 1609402-14-3
• Calculated MW 466.58
• Formulation C23H22N4O3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(NC1=NC(C2=CC=CC(NS(=O)(C3=C4C=CC=C(N(C)C)C4=CC=C3)=O)=C2)=CS1)=O
  Pathways:Cytoskeletal Signaling; Endocrinology/Hormones; Others; Metabolism
  Receptor:GRP78; HSPA5; BiP
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 45 mg/mL (96.44 mM) DMSO: 93 mg/mL (199.32 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Cerezo M et al. Cancer Cell. 2016 Jun 13;29(6):805-19.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting