• Product NameLesinurad
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityLesinurad is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors.
• Target NameOAT inhibitor
• CAS No. 878672-00-5
• Calculated MW 404.28
• Formulation C17H14BrN3O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:OC(=O)CSC1=NN=C(Br)N1C1=C2C=CC=CC2=C(C=C1)C1CC1 |c:12,14,16,19,21,t:5,7|
  Pathways:Membrane transporter/Ion channel
  Receptor:OAT1; OAT3
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 54 mg/mL (133.57 mM) DMSO: 80 mg/mL (197.88 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tan, et al.[abstract]. Arthritis Rheum 2013;65 Suppl 10 :1723

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting