• Product NameMonomethyl auristatin E (MMAE)
• Brief DescriptionInhibitors
• Purification99.47%
• Biological ActivityMonomethyl auristatin E (MMAE) is a synthetic antineoplastic agent, which is linked to a monoclonal antibody (MAB).
• Target NameMicrotubule Associated inhibitor
• CAS No. 474645-27-7
• Calculated MW 717.98
• Formulation C39H67N5O7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)C1=CC=CC=C1 |r,c:49,51,t:47|
  Pathways:Cytoskeletal Signaling
  Receptor:microtubule
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (139.27 mM)DMSO: 100 mg/mL (139.27 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Francisco JA, et al. Blood. 2003, 102(4), 1458-1465.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting