• Product NameMRT68921
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.
• Target NameAutophagy inhibitor
• CAS No. 1190379-70-4
• Calculated MW 434.6
• Formulation C25H34N6O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN1CCC2=C(C1)C=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4CCC4)C5CC5
  Pathways:Autophagy
  Receptor:ULK1; ULK2
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mLDMSO: 10 mg/mL 10 warming Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Petherick KJ, et al. J Biol Chem. 2015, 290(18), 11376-11383.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting