• Product NameMS023
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityMS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively.
• Target NameHistone Methyltransferase inhibitor
• CAS No. 1831110-54-3
• Calculated MW 287.4
• Formulation C17H25N3O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(C)OC1=CC=C(C=C1)C1=CNC=C1CN(C)CCN |c:6,8,14,t:4,11|
  Pathways:Chromatin/Epigenetic
  Receptor:PRMT1; PRMT3; PRMT4; PRMT6; PRMT8
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 57 mg/mL (198.32 mM) DMSO: 57 mg/mL (198.32 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Eram MS, et al. ACS Chem Biol. 2016, 11(3), 772-781.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting