• Product NameN6022
• Brief DescriptionInhibitors
• Purification98.24%
• Biological ActivityN6022 is a potent, selective, reversible, and efficacious S-Nitrosoglutathione reductase(GSNOR) inhibitor with IC50 of 8 nM.
• Target NameGSNOR inhibitor
• CAS No. 1208315-24-5
• Calculated MW 414.46
• Formulation C24H22N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=C(C=CC(=C1)C(N)=O)N1C(CCC(O)=O)=CC=C1C1=CC=C(C=C1)N1C=CN=C1 |c:3,5,17,19,24,26,30,32,t:1,22|
  Pathways:Metabolism
  Receptor:S-nitrosoglutathione reductase (GSNOR); S-nitrosoglutathione reductase (GSNOR)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 46 mg/mL N6022 is prepared in sterile PBS (pH 7.4)[4].
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sun X, et al. Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3671-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting