• Product NamePimavanserin
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPimavanserin is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinsons disease.
• Target Name5-HT Receptor inhibitor
• CAS No. 706782-28-7
• Calculated MW 1005.2
• Formulation C50H68F2N6O4C4H6O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1.CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1 |r,c:29,40,62,73,t:14,16,24,26,47,49,57,59|
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2A
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (99.48 mM) DMSO: 100 mg/mL (99.48 mM) Water: 100 mg/mL (99.48 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vanover KE, et al. J Pharmacol Exp Ther. 2006 May;317(2):910-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting