• Product NamePiperlongumine
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPiperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells.
• Target NameROS inhibitor
• CAS No. 20069-09-4
• Calculated MW 317.34
• Formulation C17H19NO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)N2CCC=CC2=O
  Pathways:Immunology/Inflammation
  Receptor:ROS
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 6 mg/mL warmed (18.9 mM) DMSO: 16 mg/mL (50.41 mM) warming Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jong-Lyel Roh, et al. Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer. Oncotarget. 2014; 5:9227-9238.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting