• Product NameSC1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal.
• Target NameERK inhibitor; Raf inhibitor
• CAS No. 839707-37-8
• Calculated MW 550.53
• Formulation C27H25F3N8O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN1N=C(C)C=C1NC1=NC=C2CN(C(=O)N(C)C2=N1)C1=CC(NC(=O)C2=CC=CC(=C2)C(F)(F)F)=CC=C1C |c:5,20,31,33,39,41,t:2,9,11,23,29|
  Pathways:MAPK
  Receptor:ERK1; RasGAP
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mLDMSO: 100 mg/mL (181.64 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chen S, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17266-71.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting