• Product NameRiociguat (BAY 63-2521)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityRiociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension.
• Target NameOthers
• CAS No. 625115-55-1
• Calculated MW 422.42
• Formulation C20H19FN8O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:COC(=O)N(C)C1=C(N)N=C(N=C1N)C1=NN(CC2=CC=CC=C2F)C2=NC=CC=C12 |c:6,9,11,21,23,29,t:15,19,27,31|
  Pathways:Others
  Receptor:Guanylate cyclase
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mLDMSO: 84 mg/mL (198.85 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Schermuly RT, et al. Eur Respir J. 2008, 32(4), 881-891.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting