• Product NameRS-1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityRS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 312756-74-4
• Calculated MW 524.23
• Formulation C20H16Br2N2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:BrC1=CC=C(NC(=O)C2=CC=C(Br)C(=C2)S(=O)(=O)NCC2=CC=CC=C2)C=C1 |c:13,23,25,28,t:1,3,8,10,21|
  Pathways:DNA Damage/DNA Repair
  Receptor:RAD51
  Boling pt:
  Melting pt:
  Solubility:Ethanol: <1 mg/mLDMSO: 100 mg/mL (190.75 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Song J,et al. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.Nat Commun. 2016 Jan 28;7:10548.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting