• Product NameSKL2001
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySKL2001 is a novel agonist of the Wnt/β-catenin pathway that disrupts the Axin/β-catenin interaction.
• Target NameWnt/beta-catenin agonist
• CAS No. 909089-13-0
• Calculated MW 286.29
• Formulation C14H14N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=COC(=C1)C2=CC(=NO2)C(=O)NCCCN3C=CN=C3
  Pathways:Cytoskeletal Signaling; Stem Cells
  Receptor:Wnt/β-catenin
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 57 mg/mL (199.09 mM) DMSO: 57 mg/mL (199.09 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Gwak J, et al. Cell Res. 2012, 22(1):237-47.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting