• Product NameUlixertinib (BVD-523, VRT752271)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityUlixertinib (BVD-523, VRT752271) is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Phase 1.
• Target NameERK inhibitor
• CAS No. 869886-67-9
• Calculated MW 433.33
• Formulation C21H22Cl2N4O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC(C)NC1=NC=C(Cl)C(=C1)C1=CNC(=C1)C(=O)N[C@H](CO)C1=CC(Cl)=CC=C1 |r,c:9,15,27,29,t:4,6,12,24|
  Pathways:MAPK
  Receptor:ERK2
  Boling pt:
  Melting pt:
  Solubility:Ethanol15 mg/mL (34.61 mM) DMSO: 86 mg/mL (198.46 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ward RA, et al. J Med Chem. 2015, 58(11), 4790-4801.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting