• Product NameVacquinol-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityVacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
• Target NameJNK agonist
• CAS No. 5428-80-8
• Calculated MW 425.78
• Formulation C21H21ClN2O 2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1CCNC(C1)C(C2=CC(=NC3=CC=CC=C32)C4=CC=C(C=C4)Cl)O
  Pathways:MAPK
  Receptor:MKK4
  Boling pt:
  Melting pt:
  Solubility:Ethanol<1 mg/mLDMSO: 70 mg/mL (164.4 mM)Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sander P., Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP. Oncotarget. 2017 May 23;8(21):35124-35137.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting