• Product NameWZB117
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityWZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 μM.
• Target Nametransporter inhibitor
• CAS No. 1223397-11-2
• Calculated MW 368.31
• Formulation C20H13FO6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:OC1=CC(=CC=C1)C(=O)OC1=C(OC(=O)C2=CC(O)=CC=C2)C=CC=C1F |c:3,5,11,19,21,24,26,t:1,16|
  Pathways:Metabolism
  Receptor:GLUT1
  Boling pt:
  Melting pt:
  Solubility:Ethanol73 mg/mL (198.2 mM) DMSO: 73 mg/mL (198.2 mM) Water: <1 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Liu Yet al. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.Mol Cancer Ther. 2012 Aug;11(8):1672-82.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting