• Product NameRAPGEF1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total RAPGEF1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human RAPGEF1
• Target NameRAPGEF1
• Alternative Names    C3G; GRF2
• Accession No. Swiss-Prot#:Q13905
  NCBI Gene ID:2889
  Gene Accssion:NP_005303
• UniprotQ13905
• Gene ID2889;
• Concentration 1
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• IHC dilution:1: 25-100
  

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.?

• The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 47609(RAPGEF1 Antibody) at dilution 1/35.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting