• Product NameIRX5 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsWB, IHC
• Species ReactivityHu, Ms
• SpecificityThe antibody detects endogenous levels of total IRX5 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human IRX5
• Target NameIRX5
• Alternative Names    HMMS; IRXB2; IRX-2a
• Accession No. Swiss-Prot#:P78411
  NCBI Gene ID:10265
  Gene Accssion:NP_005844
• UniprotP78411
• Gene ID10265;
• Calculated MW 50 kDa
• Concentration 0.8
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• WB dilution:1:200-1000
  IHC dilution:1: 30-150
  

This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse lung tissue lysate, Primary antibody:47665(IRX5 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 4 minutes
• The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 47665(IRX5 Antibody) at dilution 1/30.(Original magnification: 200)
• The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47665(IRX5 Antibody) at dilution 1/30.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting