• Product NameGUCY1B2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total GUCY1B2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthetic peptide of human GUCY1B2
• Target NameGUCY1B2
• Alternative Names    GC-SB2
• Accession No. Swiss-Prot#:O75343
  NCBI Gene ID:
  Gene Accssion:Hs.411573
• UniprotO75343
• Concentration 0.5
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• IHC dilution:1: 20-100
  

Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form.

• The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47785(GUCY1B2 Antibody) at dilution 1/20.(Original magnification: 200)
• The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using 47785(GUCY1B2 Antibody) at dilution 1/20.(Original magnification: 200)

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting