• Product NameCD11b/ITAM Antibody
• Host SpeciesMouse
• Clone No.4G2
• PurificationProA affinity purified
• ApplicationsIP, IF, FCM
• Species ReactivityHu, Ms
• Immunogen Descriptionpeptide
• Alternative Names    antigen CD11b (p170) antibody
  Antigen CD11b p170 antibody
  CD11 antigen like family member B antibody
  CD11 antigen-like family member B antibody
  CD11b antibody
  CD11b/CD18 antibody
  CD49d antibody
  Cell surface glycoprotein MAC-1 subunit alpha antibody
  Complement component 3 receptor 3 subunit antibody
  Complement Component Receptor 3 Alpha antibody
  Complement receptor type 3, alpha subunit antibody
  CR 3 alpha chain (CR3A) antibody
  CR 3 alpha chain antibody
  CR-3 alpha chain antibody
  CR3 antibody
  CR3A antibody
  F730045J24Rik antibody
  Integrin Alpha M antibody
  Integrin alpha M chain antibody
  Integrin alpha-M antibody
  Integrin beta 2 alpha subunit antibody
  Integrin subunit alpha M antibody
  integrin, alpha M (complement component 3 receptor 3 subunit) antibody
  ITAM_HUMAN antibody
  ITGAM antibody
  Leukocyte adhesion receptor MO1 antibody
  Ly-40 antibody
  MAC 1 antibody
  Mac-1a antibody
  MAC1 antibody
  Mac1, alpha subunit antibody
  MAC1A antibody
  Macrophage antigen alpha polypeptide antibody
  MGC117044 antibody
  Mo1, alpha subunit antibody
  MO1A antibody
  Neutrophil adherence receptor alpha M subunit antibody
  Neutrophil adherence receptor antibody
  SLEB6 antibody
  
• Accession No. Swiss-Prot#:P11215
• UniprotP11215
• Gene ID3684;
• Calculated MW 170kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• 
  
  
  IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
  FC: 1 μg per 1 x 106 cells

Integrin ?M, also designated complement component receptor-3 ?, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin ?M combines with the Integrin 2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin ?M/2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

• Western blot analysis of Integrin αM expression in human PBL whole cell lysate immunoprecipitated with Integrin αM (2LPM19c) and detected with Integrin αM (H-61).
• Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing membrane staining.
• FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1.
• FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting