• Product NameCD44 Antibody
• Host SpeciesMouse
• ClonalityMonoclonal
• Clone No.A7-1
• PurificationPeptide affinity purified
• ApplicationsWB, IHC, FC
• Species ReactivityHu
• Immunogen Descriptionpeptide
• Alternative Names    LHR antibody
  BA-1 antibody
  CD 44 antibody
  CD44 antibody
  CD44 antigen antibody
  CD44 molecule (Indian blood group) antibody
  CD44 molecule antibody
  CD44_HUMAN antibody
  CDw44 antibody
  Cell surface glycoprotein CD44 antibody
  chondroitin sulfate proteoglycan 8 antibody
  CSPG8 antibody
  ECMR-III antibody
  Epican antibody
  Extracellular matrix receptor III antibody
  GP90 lymphocyte homing/adhesion receptor antibody
  HCELL antibody
  hematopoietic cell E- and L-selectin ligand antibody
  Heparan sulfate proteoglycan antibody
  Hermes antigen antibody
  homing function and Indian blood group system antibody
  HSA antibody
  HUTCH-I antibody
  HUTCH1 antibody
  Hyaluronate receptor antibody
  IN antibody
  INLU-related p80 Glycoprotein antibody
  MC56 antibody
  MDU2 antibody
  MDU3 antibody
  MGC10468 antibody
  MIC4 antibody
  MUTCH1 antibody
  PGP-1 antibody
  PGP-I antibody
  PGP1 antibody
  Phagocytic glycoprotein 1 antibody
  Phagocytic glycoprotein I antibody
  Soluble CD44 antibody
  
• Accession No. Swiss-Prot#:P16070
• UniprotP16070
• Gene ID960;
• Calculated MW 80 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:1000
  IHC: 1:200
  
  
  FC: 1:100-1:200

CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing and tumor-cell metastasis. It mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications.

• Western blot analysis of CD44 on different cell lysates using anti- CD44 antibody at 1/500 dilution. Positive control: Line1: HUVEC Line2: HL-60 Line3: Hela Line4:SKOV3
• Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD44 antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-CD44 antibody. Counter stained with hematoxylin.
• Flow cytometric analysis of Hela cells with CD44 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti mouse IgG (FITC) was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting