• Product NameMMP2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.SI15-04
• PurificationProA affinity purified
• ApplicationsWB, IHC
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• Alternative Names    72 kDa gelatinase antibody
  72kD type IV collagenase antibody
  CLG 4 antibody
  CLG 4A antibody
  CLG4 antibody
  CLG4A antibody
  Collagenase Type 4 alpha antibody
  Collagenase type IV A antibody
  Gelatinase A antibody
  Gelatinase alpha antibody
  Gelatinase neutrophil antibody
  Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase antibody
  Matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) antibody
  Matrix Metalloproteinase 2 antibody
  Matrix metalloproteinase II antibody
  Matrix metalloproteinase-2 antibody
  MMP 2 antibody
  MMP II antibody
  MMP-2 antibody
  MMP2 antibody
  MMP2_HUMAN antibody
  MONA antibody
  Neutrophil gelatinase antibody
  PEX antibody
  TBE 1 antibody
  TBE-1 antibody
  
• Accession No. Swiss-Prot#:P08253
• UniprotP08253
• Gene ID4313;
• Calculated MW 72 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:1,000-1:2,000
  IHC: 1:50-1:200
  
  
  

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

• Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-MMP2 antibody. Counter stained with hematoxylin.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting