• Product NameEpCAM Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.SU03-32
• PurificationProA affinity purified
• ApplicationsWB, IHC
• Species ReactivityHu, Ms, Rt
• Immunogen Descriptionrecombinant protein
• Alternative Names    17 1A antibody
  323/A3 antibody
  Adenocarcinoma associated antigen antibody
  Adenocarcinoma-associated antigen antibody
  Antigen identified by monoclonal antibody
  AUA1 antibody
  AUA1 antibody
  CD326 antibody
  CD326 antigen antibody
  Cell surface glycoprotein Trop 1 antibody
  Cell surface glycoprotein Trop 2 antibody
  Cell surface glycoprotein Trop-1 antibody
  CO 17A antibody
  CO17 1A antibody
  CO17A antibody
  DIAR5 antibody
  EGP 2 antibody
  EGP antibody
  EGP2 antibody
  EGP314 antibody
  EGP40 antibody
  Ep CAM antibody
  Ep-CAM antibody
  EPCAM antibody
  EPCAM_HUMAN antibody
  EpCAM1 antibody
  Epithelial cell adhesion molecule antibody
  Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody
  Epithelial cell surface antigen antibody
  Epithelial cellular adhesion molecule antibody
  Epithelial glycoprotein 1 antibody
  Epithelial glycoprotein 314 antibody
  Epithelial glycoprotein antibody
  ESA antibody
  GA733 1 antibody
  GA733 2 antibody
  GA733-2 antibody
  gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody
  gp4 antibody
  hEGP 2 antibody
  hEGP314 antibody
  HNPCC8 antibody
  Human epithelial glycoprotein 2 antibody
  KS 1/4 antigen antibody
  KS1/4 antibody
  KSA antibody
  Ly74 antibody
  Lymphocyte antigen 74 antibody
  M1S 1 antibody
  M1S2 antibody
  M4S1 antibody
  Major gastrointestinal tumor associated protein GA733 2 antibody
  Major gastrointestinal tumor-associated protein GA733-2 antibody
  mEGP314 antibody
  Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody
  Membrane component, chromosome 4, surface marker 1 antibody
  Membrane component, chromosome 4, surface marker antibody
  MIC18 antibody
  MK 1 antibody
  Protein 289A antibody
  TACD1 antibody
  TACSTD1 antibody
  TROP1 antibody
  Tumor associated calcium signal transducer 1 antibody
  Tumor associated calcium signal transducer 2 precursor antibody
  Tumor-associated calcium signal transducer 1 antibody
  
• Accession No. Swiss-Prot#:P16422
• UniprotP16422
• Gene ID4072;
• Calculated MW 35 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:1,000-1:2,000
  IHC: 1:100-1:500
  
  
  

EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy.

• Western blot analysis of EpCAM on different lysates using anti-EpCAM antibody at 1/1,000 dilution. Positive control:
  Lane 1: HCT116
  Lane 2: SW480
• Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EpCAM antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-EpCAM antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-EpCAM antibody. Counter stained with hematoxylin.
• Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EpCAM antibody. Counter stained with hematoxylin.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting