• Product NameCytochrome P450 3A4 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JA11-33
• PurificationProA affinity purified
• ApplicationsWB, IHC, IP
• Species ReactivityHu
• Immunogen Descriptionrecombinant protein
• Alternative Names    1,8-cineole 2-exo-monooxygenase antibody
  Albendazole monooxygenase antibody
  Albendazole sulfoxidase antibody
  CP33 antibody
  CP34 antibody
  CP3A4_HUMAN antibody
  CYP3 antibody
  CYP3A antibody
  CYP3A3 antibody
  CYP3A4 antibody
  CYPIIIA3 antibody
  CYPIIIA4 antibody
  Cytochrome P450 3A3 antibody
  Cytochrome P450 3A4 antibody
  Cytochrome P450 family 3 subfamily A polypeptide 4 antibody
  Cytochrome P450 HLp antibody
  Cytochrome P450 NF-25 antibody
  Cytochrome P450 subfamily IIIA polypeptide 4 antibody
  cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody
  cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody
  Cytochrome P450-PCN1 antibody
  Glucocorticoid inducible P450 antibody
  HLP antibody
  MGC126680 antibody
  NF 25 antibody
  NF25 antibody
  Nifedipine oxidase antibody
  P450 III steroid inducible antibody
  P450 PCN1 antibody
  P450, family III antibody
  P450C3 antibody
  P450PCN1 antibody
  Quinine 3 monooxygenase antibody
  Quinine 3-monooxygenase antibody
  Taurochenodeoxycholate 6 alpha hydroxylase antibody
  Taurochenodeoxycholate 6-alpha-hydroxylase antibody
  
• Accession No. Swiss-Prot#:P08684
• UniprotP08684
• Gene ID1576;
• Calculated MW 57 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:1,000
  IHC: 1:50-1:200
  
  
  

CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt; RTI ID = 0.0 & gt; (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents.

• Western blot analysis of Cytochrome P450 3A4 on human liver tissue lysate using anti-Cytochrome P450 3A4 antibody at 1/1,000 dilution.
• Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Cytochrome P450 3A4 antibody. Counter stained with hematoxylin.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting