• Product NameInsulin Receptor R Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JM22-38
• PurificationProA affinity purified
• ApplicationsWB, IHC
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• Alternative Names    INSRR antibody
  INSRR_HUMAN antibody
  Insulin receptor related receptor precursor antibody
  Insulin receptor-related protein alpha chain antibody
  Insulin receptor-related protein beta chain antibody
  insulin receptor-related receptor antibody
  IR R antibody
  IR related receptor antibody
  IR-related receptor antibody
  IRR antibody
  Sir r antibody
  Sirr antibody
  
• Accession No. Swiss-Prot#:P14616
• UniprotP14616
• Gene ID3645;
• Calculated MW 80 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500
  IHC: 1:50-1:200
  
  
  

The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment.Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting