• Product NameWDR5 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JM73-53
• PurificationProA affinity purified
• ApplicationsWB, IHC, FC
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein
• Alternative Names    2410008O07Rik antibody
  AA408785 antibody
  AA960360 antibody
  BIG 3 antibody
  Big antibody
  BIG3 antibody
  BMP2 induced 3 kb gene protein antibody
  BMP2 induced gene, 3-KB antibody
  BMP2-induced 3-kb gene protein antibody
  MGC114572 antibody
  OTTHUMP00000162494 antibody
  SWD 3 antibody
  SWD3 antibody
  SWD3 Set1c WD40 repeat protein homolog antibody
  WD repeat containing protein 5 antibody
  WD repeat domain 5 antibody
  WD repeat protein 5 antibody
  WD repeat-containing protein 5 antibody
  WD repeat-containing protein BIG-3 antibody
  WDR 5 antibody
  Wdr5 antibody
  WDR5_HUMAN antibody
  
• Accession No. Swiss-Prot#:P61964
• UniprotP61964
• Gene ID11091;
• Calculated MW 36 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:1000
  IHC: 1:50-1:200
  
  
  FC: 1:50-1:100

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting