• Product NamePDX1 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• PurificationProA affinity purified
• ApplicationsWB, IHC, ICC/IF
• Species ReactivityHu
• Immunogen DescriptionRecombinant protein
• Alternative Names    Glucose sensitive factor antibody
  Glucose-sensitive factor antibody
  GSF antibody
  IDX 1 antibody
  IDX-1 antibody
  IDX1 antibody
  Insulin promoter factor 1 antibody
  Insulin promoter factor 1 homeodomain transcription factor antibody
  Insulin upstream factor 1 antibody
  IPF 1 antibody
  IPF-1 antibody
  IPF1 antibody
  Islet/duodenum homeobox 1 antibody
  Islet/duodenum homeobox-1 antibody
  IUF 1 antibody
  IUF-1 antibody
  IUF1 antibody
  MODY4 antibody
  Pancreas/duodenum homeobox 1 antibody
  Pancreas/duodenum homeobox protein 1 antibody
  pancreatic and duodenal homeobox P antibody
  PDX 1 antibody
  PDX-1 antibody
  PDX1 antibody
  PDX1_HUMAN antibody
  Somatostatin transactivating factor 1 antibody
  Somatostatin-transactivating factor 1 antibody
  STF 1 antibody
  STF-1 antibody
  STF1 antibody
  
• Accession No. Swiss-Prot#:P52945
• UniprotP52945
• Gene ID3651;
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• 
  IHC: 1:50-1:200
  ICC/IF: 1:50-1:200
  
  

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

• Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin.
• IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green��. The nuclear counter stain is DAPI (blue).

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting