• Product NameMMP17 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JU33-03
• PurificationProA affinity purified
• ApplicationsICC,IF,IHC,WB
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein within human MMP17 aa 1-250.
• Alternative Names    Matrix metalloproteinase 17 antibody
  Matrix metalloproteinase 17 membrane inserted antibody
  Matrix metalloproteinase-17 antibody
  Membrane type 4 matrix metalloproteinase antibody
  Membrane type matrix metalloproteinase 4 antibody
  Membrane-type matrix metalloproteinase 4 antibody
  Membrane-type-4 matrix metalloproteinase antibody
  MMP 17 antibody
  MMP-17 antibody
  Mmp17 antibody
  MMP17_HUMAN antibody
  MT MMP 4 antibody
  MT MMP4 antibody
  MT-MMP 4 antibody
  MT4 MMP antibody
  MT4-MMP antibody
  MT4MMP antibody
  MTMMP 4 antibody
  MTMMP4 antibody
  
• Accession No. Swiss-Prot#:Q9ULZ9
• UniprotQ9ULZ9
• Gene ID4326;
• Calculated MW 67 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• 
  IHC: 1:50
  ICC: 1:50
  
  

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

• Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin.
• ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
• ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting