• Product NamePARP2 Rabbit mAb
• Host SpeciesRecombinant Rabbit
• Clonality Monoclonal antibody
• Clone No.JG34-56
• PurificationProA affinity purified
• ApplicationsWB,FC
• Species ReactivityHu, Ms, Rt
• Immunogen DescriptionRecombinant protein within the C-terminus of human PARP2.
• Alternative Names    ADP ribosyltransferase like 2 antibody
  ADP-ribosyltransferase diphtheria toxin-like 2 antibody
  ADPRT 2 antibody
  ADPRT-2 antibody
  ADPRT2 antibody
  ADPRTL 2 antibody
  ADPRTL 3 antibody
  ADPRTL2 antibody
  ADPRTL3 antibody
  ARTD2 antibody
  hPARP 2 antibody
  hPARP-2 antibody
  hPARP2 antibody
  NAD(+) ADP ribosyltransferase 2 antibody
  NAD(+) ADP-ribosyltransferase 2 antibody
  pADPRT 2 antibody
  pADPRT-2 antibody
  pADPRT2 antibody
  PARP 2 antibody
  PARP-2 antibody
  PARP2 antibody
  PARP2_HUMAN antibody
  Poly (ADP ribose) polymerase family member 2 antibody
  Poly (ADP ribosyl) transferase like 2 antibody
  poly (ADP-ribose) polymerase 2 antibody
  Poly [ADP ribose] synthetase 2 antibody
  Poly [ADP-ribose] polymerase 2 antibody
  Poly(ADP ribose) synthetase antibody
  Poly[ADP-ribose] synthase 2 antibody
  
• Accession No. Swiss-Prot#:Q9UGN5
• UniprotQ9UGN5
• Gene ID10038;
• Calculated MW 66 kDa
• Formulation 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
• Storage Store at -20˚C

• WB: 1:500-1:1,000
  
  
  
  FC: 1:50-1:100

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity.

• Western blot analysis of PARP2 on SiHa and Raji cell lysates using anti-PARP2 at 1/500 dilution.
• Flow cytometric analysis of SH-SY-5Y cells with PARP2 antibody at 1/50 dilution (Fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; Yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting